MelampsoraV2, Main, Exploration, bibRecord, 000F30

RXLR effector reservoir in two Phytophthora species is dominated by a single rapidly evolving superfamily with more than 700 members

Identifieur interne : 000F30 ( Main/Exploration ); précédent : 000F29; suivant : 000F31

RXLR effector reservoir in two Phytophthora species is dominated by a single rapidly evolving superfamily with more than 700 members

Auteurs : Rays H. Y. Jiang [États-Unis, Pays-Bas] ; Sucheta Tripathy [États-Unis] ; Francine Govers [Pays-Bas] ; Brett M. Tyler [États-Unis]

Source :

Proceedings of the National Academy of Sciences of the United States of America [ 0027-8424 ] ; 2008.

RBID : PMC:2290801

Abstract

Pathogens secrete effector molecules that facilitate the infection of their hosts. A number of effectors identified in plant pathogenic Phytophthora species possess N-terminal motifs (RXLR-dEER) required for targeting these effectors into host cells. Here, we bioinformatically identify >370 candidate effector genes in each of the genomes of P. sojae and P. ramorum. A single superfamily, termed avirulence homolog (Avh) genes, accounts for most of the effectors. The Avh proteins show extensive sequence divergence but are all related and likely evolved from a common ancestor by rapid duplication and divergence. More than half of the Avh proteins contain conserved C-terminal motifs (termed W, Y, and L) that are usually arranged as a module that can be repeated up to eight times. The Avh genes belong to the most rapidly evolving part of the genome, and they are nearly always located at synteny breakpoints. The superfamily includes all experimentally identified oomycete effector and avirulence genes, and its rapid pace of evolution is consistent with a role for Avh proteins in interaction with plant hosts.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2290801

DOI: 10.1073/pnas.0709303105
PubMed: 18344324
PubMed Central: 2290801

Affiliations:

Le document en format XML

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 species is dominated by a single rapidly evolving superfamily with more than 700 members</title>
<author><name sortKey="Jiang, Rays H Y" sort="Jiang, Rays H Y" uniqKey="Jiang R" first="Rays H. Y." last="Jiang">Rays H. Y. Jiang</name>
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<wicri:cityArea>*Virginia Bioinformatics Institute, Virginia Polytechnic Institute and State University, Blacksburg</wicri:cityArea>
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">RXLR effector reservoir in two <italic>Phytophthora</italic>
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<front><div type="abstract" xml:lang="en"><p>Pathogens secrete effector molecules that facilitate the infection of their hosts. A number of effectors identified in plant pathogenic <italic>Phytophthora</italic>
 species possess N-terminal motifs (RXLR-dEER) required for targeting these effectors into host cells. Here, we bioinformatically identify >370 candidate effector genes in each of the genomes of <italic>P. sojae</italic>
 and <italic>P. ramorum</italic>
. A single superfamily, termed avirulence homolog (<italic>Avh</italic>
) genes, accounts for most of the effectors. The Avh proteins show extensive sequence divergence but are all related and likely evolved from a common ancestor by rapid duplication and divergence. More than half of the Avh proteins contain conserved C-terminal motifs (termed W, Y, and L) that are usually arranged as a module that can be repeated up to eight times. The <italic>Avh</italic>
 genes belong to the most rapidly evolving part of the genome, and they are nearly always located at synteny breakpoints. The superfamily includes all experimentally identified oomycete effector and avirulence genes, and its rapid pace of evolution is consistent with a role for Avh proteins in interaction with plant hosts.</p>
</div>
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<country name="Pays-Bas"><region name="Gueldre (province)"><name sortKey="Jiang, Rays H Y" sort="Jiang, Rays H Y" uniqKey="Jiang R" first="Rays H. Y." last="Jiang">Rays H. Y. Jiang</name>
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RXLR effector reservoir in two Phytophthora species is dominated by a single rapidly evolving superfamily with more than 700 members

RXLR effector reservoir in two Phytophthora species is dominated by a single rapidly evolving superfamily with more than 700 members

Source :

Abstract

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